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The interfacial research area of Chemical Biology has been described in various ways; most simply, it refers to the application of chemistry to the study of molecular events in biological systems. Often this involves the use of chemical tools and our knowledge of bonding, synthesis and analysis.

analitical chemistry
Analytical Chemistry

chemical chemistry Chemical Biology

inorganic chemistry Inorganic Chemistry

organic chemistry Organic Chemistry

physical chemistry Physical Chemistry

polymer science Polymer Science

supramolecular chemistry & materialsSupra- molecular Chemistry
& Materials

Relevant Research Groups

Katherine De Villiers
Research Summary:
Malaria parasites detoxify haem by forming crystalline haemozoin. Antimalarial inhibition of this process results in parasite death due to haem build-up. In light of growing parasitic resistance to commonly prescribed antimalarial drugs (e.g. chloroquine), our current focus is on:
1. understanding their molecular mechanism of action; 2. determining their effects on haemozoin biocrystallisation.
It is envisaged that such information will allow for rational design of novel antimalarial compounds. This provides an opportunity for collaborative projects with synthetic specialists.

Go to Katherine De Villiers' Research page

Relevant Research Groups

Margaret Blackie
Research Summary:
I run a multidisciplinary research group with interests in medicinal chemistry, chemical education and the philosophy of science, education and chemistry. The focus of medicinal chemistry is the rational design and synthesis of novel compounds as potential anti-malarial drugs and other tropical diseases. My interests in chemical education and philosophy of chemistry and education are complementary to one another. The primary endeavour is to develop curricula, tools and educational aids with a solid foundational philosophy in order to better prepare the next generation of chemists.
Go to Margaret Blackie's Research page
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