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The only inoculation requirement for visitors is a yellow fever vaccination certificate for those entering South Africa within six days of leaving (or traveling through) a yellow fever zone. You cannot get an inoculation upon arrival and your inoculation certificate must be dated at least ten days prior to your arrival in South Africa. Babies of one year old or less are exempt. More information can be found on the website of the Western Cape Provincial Government here.

Malaria is endemic in some parts of Mpumalanga, Northern Province and northern KwaZulu-Natal and it is advised to take precautions if you intend to visit these areas. The bilharzia parasite is present in streams, rivers, lakes and dams in some of the northern and eastern parts of the country, and visitors should avoid contact with the water in these regions. There is no immunisation against bilharzia. The closest malaria and bilharzia regions are approximately 1600 kilometres from Cape Town. Please consult your local doctor / travel clinic for further advice.